ICBO_2018_27: Semantic Interoperability: Challenges and Opportunities in Cell Type Knowledge Representation

TitleICBO_2018_27: Semantic Interoperability: Challenges and Opportunities in Cell Type Knowledge Representation
Publication TypeConference Paper
Year of Publication2018
AuthorsScheuermann, R, Aevermann, B, Keshk, M
Conference NameInternational Conference on Biomedical Ontology (ICBO 2018)
Date Published08/06/2018
PublisherInternational Conference on Biological Ontology
Keywordscell type, CL Ontology, GABAergic, glutamatergic, HCA, Interoperability, pCL, scRNAseq
Abstract

The Human Cell Atlas (HCA) and the California Institute for Regenerative Medicine’s Center of Excellence in Stem Cell Genomics (CESCG) are identifying novel cell types at a rapid pace using single cell RNA sequencing (scRNAseq). To maximize the scientific return on these discoveries, it will be critical that the data derived from these studies is translated into biological knowledge that is findable, accessible, interoperable and reproducible (FAIR). To achieve this objective, we are developing a provisional cell type ontology (pCL) where the data being gathered from experimental work is represented in a standard semantic format that can be exchanged, retrieved, and inferred over using standard approaches and tools.

URLhttp://icbo2018.cgrb.oregonstate.edu/