@conference {ICBO_2018_13, title = {ICBO_2018_13: The Identity and Mereology of Pathological Dispositions}, booktitle = {International Conference on Biomedical Ontology (ICBO 2018)}, series = {Proceedings of the International Conference on Biological Ontology (2018)}, year = {2018}, month = {08/06/2018}, publisher = {International Conference on Biological Ontology}, organization = {International Conference on Biological Ontology}, abstract = {

Diseases, risks of pathological processes and predispositions have been formalized as dispositions. The relations between those pathological dispositions, however, remain unclear. We apply here a recently developed theory of mereology and identity among dispositions to analyze such relations. In particular, we show how a framework for the identity of disposition leads to a disease being not only a disposition to a disease course, but also to each pathological process; how it avoids risk multiplicativism; and how a predisposition can be identified with a risk whose estimated probability is higher than for the risk of a reference class. We discuss how this makes predisposition always relative to a reference class, to a time-frame and to sources of risk estimates; and we clarify the nature of risk factors.

}, keywords = {disease, disposition, identity, mereology, predisposition, risk, risk factor}, url = {http://ceur-ws.org/Vol-2285/ICBO_2018_paper_13.pdf}, author = {Adrien Barton and Olivier Grenier and Jean-Francois Ethier} }